Version 5.4
Mus musculus Gene: Thop1
Summary
InnateDB Gene IDBG-176844.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thop1
Gene Name thimet oligopeptidase 1
Synonyms AI131655; AI327041; EP24.15
Species Mus musculus
Ensembl Gene ENSMUSG00000004929
Encoded Proteins
IDBP-176846
thimet oligopeptidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172009:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:81070035-81082559
Strand Forward strand
Band C1
Transcripts
ENSMUST00000005057 ENSMUSP00000005057
ENSMUST00000167658
ENSMUST00000171484
ENSMUST00000166015
ENSMUST00000166404
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0042277 peptide binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172009
View Gene Order
ENSBTAG00000020446
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04614
Renin-angiotensin system pathway
mmu05143
African trypanosomiasis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04614
Renin-angiotensin system pathway
hsa05143
African trypanosomiasis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.26995
RefSeq NM_022653
OMIM
CCDS CCDS24042
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca