Version 5.4
Mus musculus Gene: Gpt2
Summary
InnateDB Gene IDBG-177267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpt2
Gene Name glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms 4631422C05Rik; ALT2; AU014768; AU041193; C87201
Species Mus musculus
Ensembl Gene ENSMUSG00000031700
Encoded Proteins
IDBP-177269
glutamic pyruvate transaminase (alanine aminotransferase) 2
IDBP-538820
glutamic pyruvate transaminase (alanine aminotransferase) 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166123:
This gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:85492576-85527560
Strand Forward strand
Band C3
Transcripts
ENSMUST00000034136 ENSMUSP00000034136
ENSMUST00000132932 ENSMUSP00000115968
ENSMUST00000143659
ENSMUST00000140189
ENSMUST00000143846
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006103 2-oxoglutarate metabolic process
GO:0009058 biosynthetic process
GO:0042851 L-alanine metabolic process
GO:0042853 L-alanine catabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166123
View Gene Order
ENSBTAG00000002980
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_239550
Amino acid synthesis and interconversion (transamination) pathway
KEGG
mmu00250
Alanine, aspartate and glutamate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00250
Alanine, aspartate and glutamate metabolism pathway
INOH
INOH website
Glutamate Glutamine metabolism pathway
INOH website
Glycolysis Gluconeogenesis pathway
INOH website
Alanine Aspartate Asparagine metabolism pathway
PID NCI
Cross-References
SwissProt Q8BGT5
TrEMBL D6RFQ8
UniProt Splice Variant
Entrez Gene 108682
UniGene Mm.200423
RefSeq NM_173866
OMIM
CCDS CCDS22499
HPRD
IMGT
MGI ID MGI:1915391
MGI Symbol Gpt2
EMBL AC130533 AK033424 AK075894 AK076250 AK082030 BC034219 BK005128
GenPept AAH34219 BAC28282 BAC36035 BAC36274 BAC38395 DAA05290
RNA Seq Atlas 108682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca