|Mus musculus Gene: Spg21|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||spastic paraplegia 21 homolog (human)|
|Synonyms||ACP33; BM-019; C78576; D9Wsu18e; GL010; MAST;|
spastic paraplegia 21 homolog (human)
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090487:
The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 9:65460937-65488470|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|EMBL||AK009332 AK011985 AK090017 AK149930 AK150215 AK150581 AK153284 AK170666 BC099434 BC132377 BC132403 CH466522|
|GenPept||AAH99434 AAI32378 AAI32404 BAB26224 BAB27958 BAC41047 BAE29174 BAE29385 BAE29675 BAE31867 BAE41947 EDL26096|
|RNA Seq Atlas||27965|