Version 5.4
Mus musculus Gene: Xpo7
Summary
InnateDB Gene IDBG-179422.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpo7
Gene Name exportin 7
Synonyms 4930506C02Rik; BB164534; mKIAA0745; Ranbp16
Species Mus musculus
Ensembl Gene ENSMUSG00000022100
Encoded Proteins
IDBP-179424
exportin 7
IDBP-620450
exportin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130227:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70654246-70766628
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000022696 ENSMUSP00000022696
ENSMUST00000167242 ENSMUSP00000129504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005049 nuclear export signal receptor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
Biological Process
GO:0006611 protein export from nucleus
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000130227
View Gene Order
ENSBTAG00000047628
Not yet available
Cross-References
SwissProt Q9EPK7
TrEMBL
UniProt Splice Variant
Entrez Gene 65246
UniGene Mm.152987 Mm.436084
RefSeq NM_023045 XM_006519361
OMIM
CCDS CCDS36974
HPRD
IMGT
MGI ID MGI:1929705
MGI Symbol Xpo7
EMBL AJ297360 AK028303 AK032768 AK035775 AK036837 AK041768 AK122361 AK164595 BC029702
GenPept AAH29702 BAC25870 BAC28013 BAC29182 BAC29600 BAC31059 BAC65643 BAE37843 CAC17621
RNA Seq Atlas 65246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca