Version 5.4
| Mus musculus Gene: B3galt5 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||||
| InnateDB Gene | IDBG-179961.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | B3galt5 | ||||||||||
| Gene Name | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | ||||||||||
| Synonyms | 1190002B21Rik; AU045265; b3Galt-V | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000074892 | ||||||||||
| Encoded Proteins |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
|
||||||||||
| Protein Structure |
|
||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183778:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes the most probable candidate for synthesis of the type 1 Lewis antigens which are frequently found to be elevated in gastrointestinal and pancreatic cancers. The encoded protein is inactive with N-linked glycoproteins and functions in mucin glycosylation. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2012] This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants have been observed for this gene, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2013] |
||||||||||
| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 16:96235801-96319859 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | C4 | ||||||||||
| Transcripts |
|
||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||
| Gene Ontology | |||||||||||
Molecular Function |
|
||||||||||
| Biological Process |
|
||||||||||
| Cellular Component |
|
||||||||||
| Orthologs | |||||||||||
|
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||
| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME | |||||||||||
| KEGG |
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
|
||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME | |||||||||||
| KEGG |
Glycosphingolipid biosynthesis pathway
Glycosphingolipid biosynthesis pathway
|
||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q9JI67 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 93961 | ||||||||||
| UniGene | Mm.154783 Mm.401166 | ||||||||||
| RefSeq | NM_001122993 XM_006523116 XM_006523117 NM_033149 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS28356 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:2136878 | ||||||||||
| MGI Symbol | B3galt5 | ||||||||||
| EMBL | AF254738 BC057887 | ||||||||||
| GenPept | AAF86241 AAH57887 | ||||||||||
| RNA Seq Atlas | 93961 | ||||||||||