Mus musculus Gene: Trim33 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-181378.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Trim33 | ||||||||||||||||||||||
Gene Name | tripartite motif-containing 33 | ||||||||||||||||||||||
Synonyms | 8030451N04Rik; AI413936; Ecto; Tif1g | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000033014 | ||||||||||||||||||||||
Encoded Proteins |
tripartite motif-containing 33
tripartite motif-containing 33
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197323:
The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 3:103279293-103358768 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | F2.2 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway
Disease pathway
Loss of Function of SMAD4 in Cancer pathway
Signaling by TGF-beta Receptor Complex in Cancer pathway
TGFBR1 LBD Mutants in Cancer pathway
Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway
Loss of Function of TGFBR2 in Cancer pathway
SMAD2/3 MH2 Domain Mutants in Cancer pathway
TGFBR2 Kinase Domain Mutants in Cancer pathway
Gene Expression pathway
Loss of Function of TGFBR1 in Cancer pathway
TGFBR2 MSI Frameshift Mutants in Cancer pathway
SMAD4 MH2 Domain Mutants in Cancer pathway
Generic Transcription Pathway pathway
Signal Transduction pathway
TGFBR1 KD Mutants in Cancer pathway
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer pathway
Signaling by TGF-beta Receptor Complex pathway
Loss of Function of SMAD2/3 in Cancer pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TGF_beta_Receptor pathway
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REACTOME |
Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway
Generic Transcription Pathway pathway
SMAD4 MH2 Domain Mutants in Cancer pathway
Loss of Function of SMAD4 in Cancer pathway
Loss of Function of SMAD2/3 in Cancer pathway
Signaling by TGF-beta Receptor Complex in Cancer pathway
TGFBR2 MSI Frameshift Mutants in Cancer pathway
Signal Transduction pathway
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer pathway
SMAD2/3 MH2 Domain Mutants in Cancer pathway
Loss of Function of TGFBR2 in Cancer pathway
SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway
TGFBR1 KD Mutants in Cancer pathway
Loss of Function of TGFBR1 in Cancer pathway
TGFBR1 LBD Mutants in Cancer pathway
TGFBR2 Kinase Domain Mutants in Cancer pathway
Gene Expression pathway
Disease pathway
Signaling by TGF-beta Receptor Complex pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q99PP7 | ||||||||||||||||||||||
TrEMBL | E9QME5 E9QP19 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 94093 | ||||||||||||||||||||||
UniGene | Mm.195036 Mm.395021 Mm.400624 Mm.407497 Mm.408841 | ||||||||||||||||||||||
RefSeq | NM_001079830 NM_053170 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS38573 CCDS38574 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:2137357 | ||||||||||||||||||||||
MGI Symbol | Trim33 | ||||||||||||||||||||||
EMBL | AC164089 AF220138 AK129293 AY458590 | ||||||||||||||||||||||
GenPept | AAG53511 AAS10352 BAC98103 | ||||||||||||||||||||||
RNA Seq Atlas | 94093 | ||||||||||||||||||||||