InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Prkg2

Summary

InnateDB Gene

IDBG-182435.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prkg2

Gene Name

protein kinase, cGMP-dependent, type II

Synonyms

AW212535; cGK-II; CGKII; Prkgr2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029334

Encoded Proteins

IDBP-182437

protein kinase, cGMP-dependent, type II

IDBP-536059

protein kinase, cGMP-dependent, type II

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138669:
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:98929773-99037351

Strand

Reverse strand

Band

Transcripts

ENSMUST00000031277	ENSMUSP00000031277
ENSMUST00000161490	ENSMUSP00000124963
ENSMUST00000162147
ENSMUST00000162619
ENSMUST00000160765

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004692	cGMP-dependent protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0030553	cGMP binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0006468	protein phosphorylation
GO:0007623	circadian rhythm
GO:0032922	circadian regulation of gene expression
GO:0036289	peptidyl-serine autophosphorylation
GO:0072661	protein targeting to plasma membrane