Bos taurus Gene: PRKG2
Summary
InnateDB Gene IDBG-643171.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKG2
Gene Name cGMP-dependent protein kinase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002978
Encoded Proteins
cGMP-dependent protein kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138669:
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:97652569-97735626
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003877 ENSBTAP00000003877
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004692 cGMP-dependent protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007623 circadian rhythm
GO:0016310 phosphorylation
GO:0032922 circadian regulation of gene expression
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
cGMP effects pathway
Nitric oxide stimulates guanylate cyclase pathway
Platelet homeostasis pathway
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
eNOS activation and regulation pathway
Signaling by Wnt pathway
Metabolism of nitric oxide pathway
Signal Transduction pathway
Metabolism pathway
Hemostasis pathway
KEGG
Gap junction pathway
Olfactory transduction pathway
Long-term depression pathway
Salivary secretion pathway
Olfactory transduction pathway
Gap junction pathway
Long-term depression pathway
Salivary secretion pathway
INOH
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
EPO signaling pathway pathway
VEGF signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MDQ6
UniProt Splice Variant
Entrez Gene 533330
UniGene Bt.52077
RefSeq NM_001144099
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02018215
GenPept
RNA Seq Atlas 533330