InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RPL21

Summary

InnateDB Gene

IDBG-18389.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL21

Gene Name

ribosomal protein L21

Synonyms

HYPT12; L21

Species

Homo sapiens

Ensembl Gene

ENSG00000122026

Encoded Proteins

IDBP-18391

ribosomal protein L21

IDBP-18395

ribosomal protein L21

IDBP-18397

ribosomal protein L21

IDBP-18399

ribosomal protein L21

IDBP-593237

ribosomal protein L21

IDBP-704214

IDBP-704246

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L21E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:27251309-27256691

Strand

Forward strand

Band

q12.2

Transcripts

ENST00000311549	ENSP00000346027
ENST00000272274	ENSP00000351021
ENST00000319826	ENSP00000370574
ENST00000326092	ENSP00000370569
ENST00000473558
ENST00000461690	ENSP00000434298
ENST00000493317	ENSP00000471695
ENST00000466550
ENST00000483765	ENSP00000473246
ENST00000485756

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 121 experimentally validated interaction(s) in this database.

Experimentally validated
Total	121 [view]
Protein-Protein	121 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit