Version 5.4
Mus musculus Gene: Ppip5k2
Summary
InnateDB Gene IDBG-184574.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppip5k2
Gene Name diphosphoinositol pentakisphosphate kinase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040648
Encoded Proteins
IDBP-184576
diphosphoinositol pentakisphosphate kinase 2
IDBP-255113
diphosphoinositol pentakisphosphate kinase 2
IDBP-622934
diphosphoinositol pentakisphosphate kinase 2
IDBP-790194
diphosphoinositol pentakisphosphate kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145725:
Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:97706048-97770411
Strand Reverse strand
Band D
Transcripts
ENSMUST00000042509 ENSMUSP00000043401
ENSMUST00000112845 ENSMUSP00000108466
ENSMUST00000137758
ENSMUST00000152788
ENSMUST00000171129 ENSMUSP00000132889
ENSMUST00000191556 ENSMUSP00000139980
ENSMUST00000189992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity
GO:0000832 inositol hexakisphosphate 5-kinase activity
GO:0003993 acid phosphatase activity
GO:0005524 ATP binding
GO:0033857 diphosphoinositol-pentakisphosphate kinase activity
GO:0052723 inositol hexakisphosphate 1-kinase activity
GO:0052724 inositol hexakisphosphate 3-kinase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0016310 phosphorylation
GO:0016311 dephosphorylation
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145725
View Gene Order
ENSBTAG00000001485
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196482
Synthesis of pyrophosphates in the cytosol pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150188
Synthesis of pyrophosphates in the cytosol pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.220817 Mm.475423
RefSeq NM_173760 XM_006529489 XM_006529490 XM_006529491 XM_006529492 XM_006529498 XM_006529499
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca