Version 5.4
Mus musculus Gene: Paip1
Summary
InnateDB Gene IDBG-184809.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Paip1
Gene Name polyadenylate binding protein-interacting protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025451
Encoded Proteins
IDBP-184811
polyadenylate binding protein-interacting protein 1
IDBP-262891
polyadenylate binding protein-interacting protein 1
IDBP-627490
polyadenylate binding protein-interacting protein 1
IDBP-535923
polyadenylate binding protein-interacting protein 1
IDBP-627491
polyadenylate binding protein-interacting protein 1
IDBP-627494
polyadenylate binding protein-interacting protein 1
IDBP-627495
polyadenylate binding protein-interacting protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172239:
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:119428601-119458218
Strand Forward strand
Band D2.3
Transcripts
ENSMUST00000026520 ENSMUSP00000026520
ENSMUST00000109203 ENSMUSP00000104826
ENSMUST00000132304 ENSMUSP00000134617
ENSMUST00000126957 ENSMUSP00000117256
ENSMUST00000173627 ENSMUSP00000134051
ENSMUST00000174691 ENSMUSP00000134502
ENSMUST00000174533 ENSMUSP00000134365
ENSMUST00000173339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005488 binding
GO:0005515 protein binding
GO:0008494 translation activator activity
Biological Process
GO:0045727 positive regulation of translation
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000172239
View Gene Order
ENSBTAG00000020376
Not yet available
Pathways
NETPATH
REACTOME
REACT_244119
Deadenylation of mRNA pathway
REACT_233572
Gene Expression pathway
REACT_235784
Deadenylation-dependent mRNA decay pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20514
Deadenylation of mRNA pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.397051 Mm.413065 Mm.490243
RefSeq NM_001079849 NM_145457 XM_006517631 XM_006517634
OMIM
CCDS CCDS26796 CCDS36791
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca