Version 5.4
Homo sapiens Gene: ACSM1
Summary
InnateDB Gene IDBG-18511.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACSM1
Gene Name acyl-CoA synthetase medium-chain family member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166743
Encoded Proteins
IDBP-18515
acyl-CoA synthetase medium-chain family member 1
IDBP-478196
acyl-CoA synthetase medium-chain family member 1
IDBP-480086
acyl-CoA synthetase medium-chain family member 1
IDBP-479787
acyl-CoA synthetase medium-chain family member 1
IDBP-477333
acyl-CoA synthetase medium-chain family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:20623237-20698890
Strand Reverse strand
Band p12.3
Transcripts
ENST00000307493 ENSP00000301956
ENST00000519031
ENST00000519745 ENSP00000428650
ENST00000524149 ENSP00000428098
ENST00000520010 ENSP00000428047
ENST00000523065 ENSP00000428830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003996 acyl-CoA ligase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0015645 fatty acid ligase activity
GO:0046872 metal ion binding
GO:0047760 butyrate-CoA ligase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0015980 energy derivation by oxidation of organic compounds
GO:0018874 benzoate metabolic process
GO:0019395 fatty acid oxidation
GO:0019605 butyrate metabolic process
GO:0042632 cholesterol homeostasis
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033533
View Gene Order
ENSBTAG00000001417
Not yet available
Pathways
NETPATH
REACTOME
REACT_6800
Conjugation of phenylacetate with glutamine pathway
REACT_6933
Conjugation of benzoate with glycine pathway
REACT_6971
Amino Acid conjugation pathway
REACT_6959
Phase II conjugation pathway
REACT_6889
Conjugation of carboxylic acids pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
KEGG
hsa00650
Butanoate metabolism pathway
INOH
INOH website
Butanoate metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 116285
UniGene Hs.306812
RefSeq NM_052956 XM_005255084 XM_005255086 XM_006721018
HUGO HGNC:18049
OMIM 614357
CCDS CCDS10587
HPRD 12551
IMGT
EMBL
GenPept
RNA Seq Atlas 116285

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca