Version 5.4
Mus musculus Gene: Dct
Summary
InnateDB Gene IDBG-186127.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dct
Gene Name dopachrome tautomerase
Synonyms DT; slaty; slt; TRP-2; TRP2; Tyrp-2; Tyrp2
Species Mus musculus
Ensembl Gene ENSMUSG00000022129
Encoded Proteins
IDBP-186129
dopachrome tautomerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000080166:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:118012792-118052246
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000022725 ENSMUSP00000022725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004167 dopachrome isomerase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0002052 positive regulation of neuroblast proliferation
GO:0006583 melanin biosynthetic process from tyrosine
GO:0008152 metabolic process
GO:0021847 ventricular zone neuroblast division
GO:0042438 melanin biosynthetic process
GO:0043473 pigmentation
GO:0048066 developmental pigmentation
GO:0048468 cell development
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016021 integral component of membrane
GO:0033162 melanosome membrane
GO:0042470 melanosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000080166
View Gene Order
ENSBTAG00000002300
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00350
Tyrosine metabolism pathway
mmu04916
Melanogenesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00350
Tyrosine metabolism pathway
hsa04916
Melanogenesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_010024 XM_006518510
OMIM
CCDS CCDS27331
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca