Version 5.4
Mus musculus Gene: Phb2
Summary
InnateDB Gene IDBG-187510.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phb2
Gene Name prohibitin 2
Synonyms AU044498; BAP; Bap37; Bcap37; REA
Species Mus musculus
Ensembl Gene ENSMUSG00000004264
Encoded Proteins
IDBP-187512
prohibitin 2
IDBP-531952
prohibitin 2
IDBP-542378
prohibitin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000215021:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:124712336-124716950
Strand Forward strand
Band F2
Transcripts
ENSMUST00000004375 ENSMUSP00000004375
ENSMUST00000145447
ENSMUST00000124779
ENSMUST00000150847
ENSMUST00000147974 ENSMUSP00000119316
ENSMUST00000130279 ENSMUSP00000121535
ENSMUST00000143000
ENSMUST00000129422
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 73 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway
GO:0033600 negative regulation of mammary gland epithelial cell proliferation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0060744 mammary gland branching involved in thelarche
GO:0060749 mammary gland alveolus development
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000215021
View Gene Order
ENSBTAG00000013123
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.36241 Mm.470012 Mm.472984 Mm.489173
RefSeq NM_007531
OMIM
CCDS CCDS39627
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca