Mus musculus Gene: Ptpn4
Summary
InnateDB Gene IDBG-187609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptpn4
Gene Name protein tyrosine phosphatase, non-receptor type 4
Synonyms hPTP-MEG; Ptn4; PTPMEG; TEP; TEP/mPTPMEG;
Species Mus musculus
Ensembl Gene ENSMUSG00000026384
Encoded Proteins
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
protein tyrosine phosphatase, non-receptor type 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088179:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:119652467-119837613
Strand Reverse strand
Band E2.3
Transcripts
ENSMUST00000064091 ENSMUSP00000067614
ENSMUST00000166624 ENSMUSP00000126216
ENSMUST00000163435 ENSMUSP00000127713
ENSMUST00000164269 ENSMUSP00000126130
ENSMUST00000168808
ENSMUST00000163179 ENSMUSP00000130841
ENSMUST00000168429 ENSMUSP00000130299
ENSMUST00000166422 ENSMUSP00000129180
ENSMUST00000168303 ENSMUSP00000129521
ENSMUST00000164086 ENSMUSP00000127998
ENSMUST00000163621 ENSMUSP00000130808
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0009898 cytoplasmic side of plasma membrane
GO:0019898 extrinsic component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_019933 XM_006529253 XM_006529254 XM_006529255 XM_006529256
OMIM
CCDS CCDS15227
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas