Version 5.4
Mus musculus Gene: Ptprq
Summary
InnateDB Gene IDBG-189187.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptprq
Gene Name protein tyrosine phosphatase, receptor type, Q
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035916
Encoded Proteins
IDBP-189189
protein tyrosine phosphatase, receptor type, Q
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139304:
This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus are associated with hearing loss. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:107517360-107720027
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000050702 ENSMUSP00000058572
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042472 inner ear morphogenesis
GO:0045598 regulation of fat cell differentiation
GO:0050885 neuromuscular process controlling balance
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0060116 vestibular receptor cell morphogenesis
Cellular Component
GO:0016021 integral component of membrane
GO:0032421 stereocilium bundle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139304
View Gene Order
ENSBTAG00000026977
Not yet available
Cross-References
SwissProt P0C5E4
TrEMBL
UniProt Splice Variant
Entrez Gene 237523
UniGene Mm.391418
RefSeq NM_001081432 XM_006513635 XM_006513636
OMIM
CCDS CCDS36051
HPRD
IMGT
MGI ID MGI:1096349
MGI Symbol Ptprq
EMBL AC021642 AC123948 AC155168
GenPept
RNA Seq Atlas 237523

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca