Version 5.4
Mus musculus Gene: Ambra1
Summary
InnateDB Gene IDBG-191639.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ambra1
Gene Name autophagy/beclin 1 regulator 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040506
Encoded Proteins
IDBP-191641
autophagy/beclin 1 regulator 1
IDBP-191643
autophagy/beclin 1 regulator 1
IDBP-191645
autophagy/beclin 1 regulator 1
IDBP-258387
autophagy/beclin 1 regulator 1
IDBP-258389
autophagy/beclin 1 regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110497:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:91730134-91918849
Strand Forward strand
Band E1
Transcripts
ENSMUST00000099712 ENSMUSP00000097299
ENSMUST00000045699 ENSMUSP00000048898
ENSMUST00000045705 ENSMUSP00000049258
ENSMUST00000111317 ENSMUSP00000106949
ENSMUST00000111316 ENSMUSP00000106948
ENSMUST00000124132
ENSMUST00000156496
ENSMUST00000133490
ENSMUST00000142224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006914 autophagy
GO:0008285 negative regulation of cell proliferation
GO:0021915 neural tube development
GO:0030154 cell differentiation
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005776 autophagic vacuole
GO:0005930 axoneme
GO:0045335 phagocytic vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110497
View Gene Order
ENSBTAG00000004282
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.436667
RefSeq NM_001080754 NM_172669 XM_006499253
OMIM
CCDS CCDS38179 CCDS38180
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca