Version 5.4
Homo sapiens Gene: AMBRA1
Summary
InnateDB Gene IDBG-41755.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMBRA1
Gene Name autophagy/beclin-1 regulator 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000110497
Encoded Proteins
IDBP-41759
autophagy/beclin-1 regulator 1
IDBP-372492
autophagy/beclin-1 regulator 1
IDBP-598532
autophagy/beclin-1 regulator 1
IDBP-596961
autophagy/beclin-1 regulator 1
IDBP-590264
autophagy/beclin-1 regulator 1
IDBP-596100
autophagy/beclin-1 regulator 1
IDBP-600343
autophagy/beclin-1 regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:46396414-46594125
Strand Reverse strand
Band p11.2
Transcripts
ENST00000314845 ENSP00000318313
ENST00000458649 ENSP00000415327
ENST00000533727 ENSP00000433372
ENST00000534300 ENSP00000431926
ENST00000526545 ENSP00000434895
ENST00000528950 ENSP00000433945
ENST00000529553
ENST00000529963
ENST00000529558
ENST00000531542
ENST00000524783
ENST00000526606 ENSP00000431486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 47 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006914 autophagy
GO:0008285 negative regulation of cell proliferation
GO:0021915 neural tube development
GO:0030154 cell differentiation
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005737 cytoplasm
GO:0005776 autophagic vacuole
GO:0005930 axoneme
GO:0031410 cytoplasmic vesicle
GO:0045335 phagocytic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040506
View Gene Order
ENSBTAG00000004282
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654644 Hs.738748
RefSeq NM_001267782 NM_001267783 NM_001300731 NM_017749 XM_005253009 XM_005253011 XM_005253012 XM_005253014 XM_006718259
HUGO
OMIM
CCDS CCDS31475 CCDS58132 CCDS73281
HPRD 10975
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca