Mus musculus Gene: Grip1 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-192287.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Grip1 | ||||||||||||||||||||||
Gene Name | glutamate receptor interacting protein 1 | ||||||||||||||||||||||
Synonyms | 4931400F03Rik; eb; GRIP | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000034813 | ||||||||||||||||||||||
Encoded Proteins |
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
glutamate receptor interacting protein 1
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene encodes a protein containing multiple PDZ (post synaptic density protein, Drosophila disc large tumor suppressor, and zonula occludens-1 protein) domains. The encoded protein acts as a mediator between cytoskeletal and membrane proteins, particularly in neuronal cells, and facilitates complex formation at the cell membrane. Mutation of this gene can cause embryonic lethality resulting from defects of the dermo-epidermal junction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 10:119454034-120087261 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | D2 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Neuronal System pathway
Trafficking of GluR2-containing AMPA receptors pathway
Trafficking of AMPA receptors pathway
Transmission across Chemical Synapses pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Trafficking of GluR2-containing AMPA receptors pathway
Trafficking of AMPA receptors pathway
Neuronal System pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | Q925T6 | ||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 74053 | ||||||||||||||||||||||
UniGene | Mm.196692 Mm.489493 | ||||||||||||||||||||||
RefSeq | NM_028736 XM_006514231 XM_006514232 XM_006514234 XM_006514235 XM_006514238 XM_006514239 XM_006514242 NM_001277292 NM_001277293 NM_001277294 NM_001277295 NM_130891 NM_133442 XM_006514233 XM_006514236 XM_006514237 XM_006514241 XM_006514244 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS24202 CCDS36071 CCDS36072 CCDS70111 CCDS70112 CCDS70113 CCDS70114 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1921303 | ||||||||||||||||||||||
MGI Symbol | Grip1 | ||||||||||||||||||||||
EMBL | AB051560 AB051561 AB051562 AK029905 AK043821 | ||||||||||||||||||||||
GenPept | BAB46929 BAB46930 BAB46931 BAC26668 BAC31662 | ||||||||||||||||||||||
RNA Seq Atlas | 74053 | ||||||||||||||||||||||