Version 5.4
| Mus musculus Gene: St8sia2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-192862.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | St8sia2 | ||||||||||||||||||
| Gene Name | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | ||||||||||||||||||
| Synonyms | AI323367; Siat8b; ST8SiaII; STX | ||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000025789 | ||||||||||||||||||
| Encoded Proteins |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140557:
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 7:73939119-74013682 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | D1 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
N-Glycan antennae elongation pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
NCAM1 interactions pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Axon guidance pathway
Asparagine N-linked glycosylation pathway
Developmental Biology pathway
NCAM signaling for neurite out-growth pathway
Sialic acid metabolism pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
N-Glycan antennae elongation pathway
Transport to the Golgi and subsequent modification pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
NCAM1 interactions pathway
NCAM signaling for neurite out-growth pathway
Developmental Biology pathway
Post-translational protein modification pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Synthesis of substrates in N-glycan biosythesis pathway
Axon guidance pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
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| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O35696 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 20450 | ||||||||||||||||||
| UniGene | Mm.413695 Mm.4954 | ||||||||||||||||||
| RefSeq | NM_009181 XM_006540731 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS21365 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | MGI:106020 | ||||||||||||||||||
| MGI Symbol | St8sia2 | ||||||||||||||||||
| EMBL | BC096546 CH466543 X83562 X99646 X99647 X99648 X99649 X99650 X99651 | ||||||||||||||||||
| GenPept | AAH96546 CAA58548 CAA67965 EDL07123 | ||||||||||||||||||
| RNA Seq Atlas | 20450 | ||||||||||||||||||