Mus musculus Gene: Elovl6
Summary
InnateDB Gene IDBG-193382.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elovl6
Gene Name ELOVL family member 6, elongation of long chain fatty acids (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041220
Encoded Proteins
ELOVL family member 6, elongation of long chain fatty acids (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170522:
Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:129532386-129638495
Strand Forward strand
Band G3
Transcripts
ENSMUST00000071402 ENSMUSP00000071351
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0019367 fatty acid elongation, saturated fatty acid
GO:0030497 fatty acid elongation
GO:0042759 long-chain fatty acid biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Synthesis of very long-chain fatty acyl-CoAs pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Fatty Acyl-CoA Biosynthesis pathway
Triglyceride Biosynthesis pathway
KEGG
Biosynthesis of unsaturated fatty acids pathway
Fatty acid elongation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Synthesis of very long-chain fatty acyl-CoAs pathway
Fatty Acyl-CoA Biosynthesis pathway
Triglyceride Biosynthesis pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
KEGG
Biosynthesis of unsaturated fatty acids pathway
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt Q920L5
TrEMBL
UniProt Splice Variant
Entrez Gene 170439
UniGene Mm.314113 Mm.475605
RefSeq NM_130450 XM_006501074 XM_006501075
OMIM
CCDS CCDS38632
HPRD
IMGT
MGI ID MGI:2156528
MGI Symbol Elovl6
EMBL AB072039 AF480860 AK029029 AK167373 AY053453 BC051041 BC098492 BC100576
GenPept AAH51041 AAH98492 AAI00577 AAL14239 AAM13450 BAB68544 BAC26252 BAE39469
RNA Seq Atlas 170439