InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp2c1

Summary

InnateDB Gene

IDBG-195296.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp2c1

Gene Name

ATPase, Ca++-sequestering

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032570

Encoded Proteins

IDBP-195298

ATPase, Ca++-sequestering

IDBP-195300

ATPase, Ca++-sequestering

IDBP-255728

ATPase, Ca++-sequestering

IDBP-625060

ATPase, Ca++-sequestering

IDBP-742433

IDBP-742120

IDBP-741976

IDBP-742447

IDBP-742598

IDBP-741999

IDBP-741964

IDBP-741993

IDBP-742622

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000017260:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:105403539-105527319

Strand

Reverse strand

Band

Transcripts

ENSMUST00000085133	ENSMUSP00000082220
ENSMUST00000038118	ENSMUSP00000039103
ENSMUST00000112558	ENSMUSP00000108177
ENSMUST00000112557
ENSMUST00000163879	ENSMUSP00000129617
ENSMUST00000176770	ENSMUSP00000134764
ENSMUST00000176787
ENSMUST00000176656
ENSMUST00000177293	ENSMUSP00000135802
ENSMUST00000175697
ENSMUST00000177074	ENSMUSP00000135646
ENSMUST00000177334	ENSMUSP00000134902
ENSMUST00000176036	ENSMUSP00000135010
ENSMUST00000177000
ENSMUST00000177189
ENSMUST00000176363	ENSMUSP00000135170
ENSMUST00000176190	ENSMUSP00000135320
ENSMUST00000176390	ENSMUSP00000135261
ENSMUST00000176651	ENSMUSP00000135732
ENSMUST00000176960
ENSMUST00000190802
ENSMUST00000186495

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004871	signal transducer activity
GO:0005388	calcium-transporting ATPase activity
GO:0005509	calcium ion binding
GO:0005524	ATP binding
GO:0015410	manganese-transporting ATPase activity
GO:0019829	cation-transporting ATPase activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0006816	calcium ion transport
GO:0006828	manganese ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0007165	signal transduction
GO:0008152	metabolic process
GO:0008544	epidermis development
GO:0016339	calcium-dependent cell-cell adhesion
GO:0030026	cellular manganese ion homeostasis
GO:0031532	actin cytoskeleton reorganization
GO:0032468	Golgi calcium ion homeostasis
GO:0032472	Golgi calcium ion transport
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070588	calcium ion transmembrane transport
GO:0071421	manganese ion transmembrane transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0032580	Golgi cisterna membrane