Bos taurus Gene: ATP2C1
Summary
InnateDB Gene IDBG-639111.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP2C1
Gene Name Calcium-transporting ATPase type 2C member 1
Synonyms SPCA;
Species Bos taurus
Ensembl Gene ENSBTAG00000011626
Encoded Proteins
Calcium-transporting ATPase type 2C member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000017260:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:140368053-140522639
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015441 ENSBTAP00000015441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004871 signal transducer activity
GO:0005388 calcium-transporting ATPase activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0015410 manganese-transporting ATPase activity
GO:0016787 hydrolase activity
GO:0019829 cation-transporting ATPase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0006828 manganese ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007165 signal transduction
GO:0008152 metabolic process
GO:0008544 epidermis development
GO:0016339 calcium-dependent cell-cell adhesion
GO:0030026 cellular manganese ion homeostasis
GO:0031532 actin cytoskeleton reorganization
GO:0032468 Golgi calcium ion homeostasis
GO:0032472 Golgi calcium ion transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070588 calcium ion transmembrane transport
GO:0071421 manganese ion transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
Ion channel transport pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.269
RefSeq NM_175785
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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