Version 5.4
Mus musculus Gene: Mybbp1a
Summary
InnateDB Gene IDBG-196765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mybbp1a
Gene Name MYB binding protein (P160) 1a
Synonyms AL024407; AU019902; P160; p160MBP; p67MBP
Species Mus musculus
Ensembl Gene ENSMUSG00000040463
Encoded Proteins
IDBP-196767
MYB binding protein (P160) 1a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132382:
This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:72441355-72451768
Strand Forward strand
Band B4
Transcripts
ENSMUST00000045633 ENSMUSP00000044827
ENSMUST00000152894
ENSMUST00000162048
ENSMUST00000156833
ENSMUST00000134119
ENSMUST00000144374
ENSMUST00000155995
ENSMUST00000144923
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 71 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006261 DNA-dependent DNA replication
GO:0006351 transcription, DNA-templated
GO:0006913 nucleocytoplasmic transport
GO:0022904 respiratory electron transport chain
GO:0042149 cellular response to glucose starvation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0071158 positive regulation of cell cycle arrest
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0042564 NLS-dependent protein nuclear import complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132382
View Gene Order
ENSBTAG00000007430
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.147946 Mm.413075
RefSeq NM_016776
OMIM
CCDS CCDS24986
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca