Mus musculus Gene: Cs
Summary
InnateDB Gene IDBG-197262.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cs
Gene Name citrate synthase
Synonyms 2610511A05Rik; 9030605P22Rik; ahl4; BB234005; Cis;
Species Mus musculus
Ensembl Gene ENSMUSG00000005683
Encoded Proteins
citrate synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000062485:
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:128337832-128362479
Strand Forward strand
Band D3
Transcripts
ENSMUST00000005826 ENSMUSP00000005826
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004108 citrate (Si)-synthase activity
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0044262 cellular carbohydrate metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
KEGG
Citrate cycle (TCA cycle) pathway
Glyoxylate and dicarboxylate metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
Metabolism of proteins pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Mitochondrial protein import pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
KEGG
Citrate cycle (TCA cycle) pathway
Glyoxylate and dicarboxylate metabolism pathway
INOH
Citrate cycle pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9CZU6
TrEMBL Q0QEL9
UniProt Splice Variant
Entrez Gene 12974
UniGene Mm.413891
RefSeq NM_026444
OMIM
CCDS CCDS24273
HPRD
IMGT
MGI ID MGI:88529
MGI Symbol Cs
EMBL AB056479 AK012151 AK145643 AK149990 AK163273 AK166814 AK167125 BC013554 BC029754 DQ403125
GenPept AAH13554 AAH29754 ABD77258 BAB28063 BAB63945 BAE26560 BAE29218 BAE37268 BAE39041 BAE39273
RNA Seq Atlas 12974