Bos taurus Gene: CS
Summary
InnateDB Gene IDBG-636112.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CS
Gene Name Citrate synthase, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004371
Encoded Proteins
Citrate synthase, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000062485:
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:57366008-57389596
Strand Forward strand
Band
Transcripts
ENSBTAT00000005730 ENSBTAP00000005730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004108 citrate (Si)-synthase activity
GO:0016740 transferase activity
GO:0044822 poly(A) RNA binding
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
GO:0044262 cellular carbohydrate metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
Metabolism of proteins pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Mitochondrial protein import pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
KEGG
Citrate cycle (TCA cycle) pathway
Glyoxylate and dicarboxylate metabolism pathway
Citrate cycle (TCA cycle) pathway
Glyoxylate and dicarboxylate metabolism pathway
INOH
Citrate cycle pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q29RK1
TrEMBL
UniProt Splice Variant
Entrez Gene 280682
UniGene Bt.106319 Bt.106917 Bt.60921 Bt.77178
RefSeq NM_001044721
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114138
GenPept AAI14139
RNA Seq Atlas 280682
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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