Version 5.4
Mus musculus Gene: Tctn1
Summary
InnateDB Gene IDBG-198038.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tctn1
Gene Name tectonic family member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038593
Encoded Proteins
IDBP-257492
tectonic family member 1
IDBP-531979
tectonic family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204852:
This gene encodes a member of the tectonic family of secreted and transmembrane proteins. The orthologous gene in mouse is required for formation of most ventral cell types. It functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:122241287-122264460
Strand Reverse strand
Band F
Transcripts
ENSMUST00000111738 ENSMUSP00000107367
ENSMUST00000141281 ENSMUSP00000114820
ENSMUST00000137118
ENSMUST00000176677
ENSMUST00000177148
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001841 neural tube formation
GO:0008589 regulation of smoothened signaling pathway
GO:0021523 somatic motor neuron differentiation
GO:0021537 telencephalon development
GO:0021904 dorsal/ventral neural tube patterning
GO:0021956 central nervous system interneuron axonogenesis
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0035869 ciliary transition zone
GO:0036038 TCTN-B9D complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204852
View Gene Order
ENSBTAG00000009208
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.375934
RefSeq NM_001039153
OMIM
CCDS CCDS39254
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca