Version 5.4
Mus musculus Gene: Eif4g3
Summary
InnateDB Gene IDBG-199269.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif4g3
Gene Name eukaryotic translation initiation factor 4 gamma, 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000028760
Encoded Proteins
IDBP-199271
eukaryotic translation initiation factor 4 gamma, 3
IDBP-199273
eukaryotic translation initiation factor 4 gamma, 3
IDBP-199275
eukaryotic translation initiation factor 4 gamma, 3
IDBP-270034
eukaryotic translation initiation factor 4 gamma, 3
IDBP-270036
eukaryotic translation initiation factor 4 gamma, 3
IDBP-535366
eukaryotic translation initiation factor 4 gamma, 3
IDBP-537419
eukaryotic translation initiation factor 4 gamma, 3
IDBP-535285
eukaryotic translation initiation factor 4 gamma, 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075151:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:137993022-138208508
Strand Forward strand
Band D3
Transcripts
ENSMUST00000084215 ENSMUSP00000081233
ENSMUST00000084214 ENSMUSP00000081232
ENSMUST00000058133 ENSMUSP00000059465
ENSMUST00000105831 ENSMUSP00000101457
ENSMUST00000105830 ENSMUSP00000101456
ENSMUST00000139759 ENSMUSP00000116927
ENSMUST00000127707
ENSMUST00000132194
ENSMUST00000155142 ENSMUSP00000122972
ENSMUST00000140796 ENSMUSP00000115946
ENSMUST00000133902
ENSMUST00000135745
ENSMUST00000140317
ENSMUST00000148074
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0006413 translational initiation
GO:0007283 spermatogenesis
GO:0045727 positive regulation of translation
GO:0060903 positive regulation of meiosis I
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075151
View Gene Order
ENSBTAG00000040215
Not yet available
Pathways
NETPATH
REACTOME
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_198535
Antiviral mechanism by IFN-stimulated genes pathway
REACT_198533
ISG15 antiviral mechanism pathway
REACT_230745
Immune System pathway
REACT_198666
Interferon Signaling pathway
KEGG
mmu05416
Viral myocarditis pathway
mmu03013
RNA transport pathway
INOH
INOH website
Insulin receptor signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115831
ISG15 antiviral mechanism pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
hsa05416
Viral myocarditis pathway
hsa03013
RNA transport pathway
INOH
INOH website
Insulin receptor signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.268903 Mm.407375 Mm.409767
RefSeq NM_001256195 NM_001256198 NM_172703 XM_006538775 XM_006538786 XM_006538793 XM_006538794 XM_006538795 XM_006538796
OMIM
CCDS CCDS38926
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca