Version 5.4
Mus musculus Gene: Lrrfip2
Summary
InnateDB Gene IDBG-202692.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrrfip2
Gene Name leucine rich repeat (in FLII) interacting protein 2
Synonyms 5133400F20Rik; AI850587
Species Mus musculus
Ensembl Gene ENSMUSG00000032497
Encoded Proteins
IDBP-202694
leucine rich repeat (in FLII) interacting protein 2
IDBP-202696
leucine rich repeat (in FLII) interacting protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21220426
Lrrfip2, upon phosphorylation, interacts with Myd88 during LPS stimulation and induces NFKB activity.
InnateDB Annotation from Orthologs
Summary
PMID 21220426
[Homo sapiens] LRRFIP2, when phosphorylated at serine 202, interacts with MYD88 during LPS stimulation to induces NFKB activity.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000093167:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:111118111-111225668
Strand Forward strand
Band F3
Transcripts
ENSMUST00000098340 ENSMUSP00000095944
ENSMUST00000035078 ENSMUSP00000035078
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030275 LRR domain binding
Biological Process
GO:0016055 Wnt signaling pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000093167
View Gene Order
ENSBTAG00000016760
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.302287
RefSeq NM_001164838 NM_027742
OMIM
CCDS CCDS23583 CCDS52941
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca