Mus musculus Gene: Ascl3
Summary
InnateDB Gene IDBG-206250.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ascl3
Gene Name achaete-scute complex homolog 3 (Drosophila)
Synonyms bHLHa42; Sgn1;
Species Mus musculus
Ensembl Gene ENSMUSG00000035951
Encoded Proteins
achaete-scute complex homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176009:
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:109727465-109731732
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000035372 ENSMUSP00000037702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9JJR7
TrEMBL
UniProt Splice Variant
Entrez Gene 56787
UniGene Mm.29275
RefSeq NM_020051
OMIM
CCDS CCDS21737
HPRD
IMGT
MGI ID MGI:1928820
MGI Symbol Ascl3
EMBL AB046448 AJ277605 AJ400878 BC104346 BC104347
GenPept AAI04347 AAI04348 BAB83911 CAB92296 CAC37689
RNA Seq Atlas 56787