Version 5.4
Mus musculus Gene: Ampd3
Summary
InnateDB Gene IDBG-206642.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ampd3
Gene Name adenosine monophosphate deaminase 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000005686
Encoded Proteins
IDBP-206644
adenosine monophosphate deaminase 3
IDBP-537169
adenosine monophosphate deaminase 3
IDBP-534786
adenosine monophosphate deaminase 3
IDBP-540143
adenosine monophosphate deaminase 3
IDBP-620016
adenosine monophosphate deaminase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the adenosine and AMP deaminases family. The encoded protein is an AMP deaminase involved in nucleotide and energy metabolism in erythrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:110768206-110812405
Strand Forward strand
Band E3
Transcripts
ENSMUST00000005829 ENSMUSP00000005829
ENSMUST00000106686
ENSMUST00000143786 ENSMUSP00000120983
ENSMUST00000147587 ENSMUSP00000121238
ENSMUST00000148292 ENSMUSP00000122657
ENSMUST00000170374 ENSMUSP00000130495
ENSMUST00000176487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006188 IMP biosynthetic process
GO:0032264 IMP salvage
GO:0046031 ADP metabolic process
GO:0046033 AMP metabolic process
GO:0046034 ATP metabolic process
GO:0097009 energy homeostasis
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000133805
View Gene Order
ENSBTAG00000015821
Not yet available
Pathways
NETPATH
REACTOME
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_244050
Purine salvage pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1923
Purine salvage pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL D3YU73 D3Z4N3
UniProt Splice Variant
Entrez Gene 11717
UniGene Mm.3238 Mm.445600
RefSeq NM_001276301 NM_009667 XM_006507215 XM_006507216 XM_006507218 XM_006507219 XM_006507220 XM_006507221 XM_006507222
OMIM
CCDS CCDS21747
HPRD
IMGT
MGI ID MGI:1096344
MGI Symbol Ampd3
EMBL AC122844
GenPept
RNA Seq Atlas 11717

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca