Version 5.4
Mus musculus Gene: Mylk2
Summary
InnateDB Gene IDBG-209914.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mylk2
Gene Name myosin, light polypeptide kinase 2, skeletal muscle
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027470
Encoded Proteins
IDBP-209916
myosin, light polypeptide kinase 2, skeletal muscle
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101306:
This gene encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:152911352-152923068
Strand Forward strand
Band H1
Transcripts
ENSMUST00000028970 ENSMUSP00000028970
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004687 myosin light chain kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006941 striated muscle contraction
GO:0007274 neuromuscular synaptic transmission
GO:0010628 positive regulation of gene expression
GO:0014816 satellite cell differentiation
GO:0018107 peptidyl-threonine phosphorylation
GO:0032971 regulation of muscle filament sliding
GO:0035914 skeletal muscle cell differentiation
GO:0046777 protein autophosphorylation
GO:0055007 cardiac muscle cell differentiation
GO:0055008 cardiac muscle tissue morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101306
View Gene Order
ENSBTAG00000014930
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04020
Calcium signaling pathway pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04510
Focal adhesion pathway
mmu04270
Vascular smooth muscle contraction pathway
mmu04971
Gastric acid secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04510
Focal adhesion pathway
hsa04020
Calcium signaling pathway pathway
hsa04270
Vascular smooth muscle contraction pathway
hsa04971
Gastric acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250604
RefSeq NM_001081044
OMIM
CCDS CCDS38282
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca