Version 5.4
Homo sapiens Gene: SKIV2L2
Summary
InnateDB Gene IDBG-21081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SKIV2L2
Gene Name superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Synonyms Dob1; fSAP118; KIAA0052; Mtr4
Species Homo sapiens
Ensembl Gene ENSG00000039123
Encoded Proteins
IDBP-21085
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
IDBP-480673
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
IDBP-484754
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
IDBP-476538
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:55307760-55425581
Strand Forward strand
Band q11.2
Transcripts
ENST00000230640 ENSP00000230640
ENST00000504388
ENST00000506750 ENSP00000425042
ENST00000503165
ENST00000504997
ENST00000505565 ENSP00000422125
ENST00000502953
ENST00000518955
ENST00000508716 ENSP00000426641
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
Experimentally validated
Total 45 [view]
Protein-Protein 45 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0000460 maturation of 5.8S rRNA
Cellular Component
GO:0000178 exosome (RNase complex)
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000016018
View Gene Order
ENSBTAG00000010518
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D6REC7
UniProt Splice Variant
Entrez Gene 23517
UniGene Hs.274531
RefSeq NM_015360
HUGO HGNC:18734
OMIM
CCDS CCDS3967
HPRD 13777
IMGT
EMBL AC010480 AC020728
GenPept
RNA Seq Atlas 23517

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca