Version 5.4
Mus musculus Gene: Ddx42
Summary
InnateDB Gene IDBG-213407.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx42
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Synonyms 1810047H21Rik; AW319508; AW556242; B430002H05Rik; RHELP; RNAHP; SF3b125
Species Mus musculus
Ensembl Gene ENSMUSG00000020705
Encoded Proteins
IDBP-213409
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198231:
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:106216926-106249139
Strand Forward strand
Band E1
Transcripts
ENSMUST00000021046 ENSMUSP00000021046
ENSMUST00000152860
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0008104 protein localization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015030 Cajal body
GO:0016020 membrane
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198231
View Gene Order
ENSBTAG00000021058
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt Q810A7
TrEMBL Q9CTM9
UniProt Splice Variant
Entrez Gene 72047
UniGene Mm.368407 Mm.41367 Mm.473458
RefSeq NM_028074 XM_006534281
OMIM
CCDS CCDS48956
HPRD
IMGT
MGI ID MGI:1919297
MGI Symbol Ddx42
EMBL AK007805 AK021013 AK049311 AK169816 AK171730 AL604045 BC043036
GenPept AAH43036 BAB25270 BAB32277 BAC33675 BAE41388 BAE42635 CAM23778
RNA Seq Atlas 72047

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca