Version 5.4
Mus musculus Gene: Fscn2
Summary
InnateDB Gene IDBG-214785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fscn2
Gene Name fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025380
Encoded Proteins
IDBP-214787
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186765:
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120361534-120368168
Strand Forward strand
Band E2
Transcripts
ENSMUST00000026445 ENSMUSP00000026445
ENSMUST00000152556
ENSMUST00000130476
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008083 growth factor activity
GO:0030674 protein binding, bridging
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0042462 eye photoreceptor cell development
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0032420 stereocilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186765
View Gene Order
ENSBTAG00000024932
Not yet available
Cross-References
SwissProt Q32M02
TrEMBL
UniProt Splice Variant
Entrez Gene 238021
UniGene Mm.481403
RefSeq NM_172802
OMIM
CCDS CCDS25731
HPRD
IMGT
MGI ID MGI:2443337
MGI Symbol Fscn2
EMBL AK050002 AL669855 BC109356 BC109357 CH466558
GenPept AAI09357 AAI09358 BAC34026 CAM27038 EDL34739
RNA Seq Atlas 238021

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca