Mus musculus Gene: Fscn2
Summary
InnateDB Gene IDBG-214785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fscn2
Gene Name fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000025380
Encoded Proteins
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186765:
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120361534-120368168
Strand Forward strand
Band E2
Transcripts
ENSMUST00000026445 ENSMUSP00000026445
ENSMUST00000152556
ENSMUST00000130476
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008083 growth factor activity
GO:0030674 protein binding, bridging
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0042462 eye photoreceptor cell development
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0032420 stereocilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.481403
RefSeq NM_172802
OMIM
CCDS CCDS25731
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas