Version 5.4
Homo sapiens Gene: SEPT11
Summary
InnateDB Gene IDBG-25655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEPT11
Gene Name septin 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138758
Encoded Proteins
IDBP-25657
septin 11
IDBP-476779
septin 11
IDBP-481571
septin 11
IDBP-474376
septin 11
IDBP-479706
septin 11
IDBP-482542
septin 11
IDBP-481871
septin 11
IDBP-480132
septin 11
IDBP-481257
septin 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:76949703-77040384
Strand Forward strand
Band q21.1
Transcripts
ENST00000264893 ENSP00000264893
ENST00000502584 ENSP00000426344
ENST00000510641 ENSP00000420839
ENST00000505788 ENSP00000424925
ENST00000512575
ENST00000510515 ENSP00000422896
ENST00000504637 ENSP00000425262
ENST00000512778 ENSP00000422047
ENST00000512333
ENST00000504460
ENST00000506047
ENST00000506731 ENSP00000423103
ENST00000502401 ENSP00000424122
ENST00000513373
ENST00000513697
ENST00000515671
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0051291 protein heterooligomerization
GO:0051301 cell division
Cellular Component
GO:0001725 stress fiber
GO:0030054 cell junction
GO:0030424 axon
GO:0031105 septin complex
GO:0043197 dendritic spine
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058013
View Gene Order
ENSBTAG00000021372
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.635257
RefSeq NM_018243 XM_005263120 XM_006714259
HUGO
OMIM
CCDS CCDS34018
HPRD 08555
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca