Homo sapiens Gene: SOX15
Summary
InnateDB Gene IDBG-26076.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX15
Gene Name SRY (sex determining region Y)-box 15
Synonyms SOX20; SOX26; SOX27;
Species Homo sapiens
Ensembl Gene ENSG00000129194
Encoded Proteins
SRY (sex determining region Y)-box 15
SRY (sex determining region Y)-box 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:7588178-7590170
Strand Reverse strand
Band p13.1
Transcripts
ENST00000250055 ENSP00000355354
ENST00000538513 ENSP00000439311
ENST00000570788 ENSP00000458286
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008584 male gonad development
GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration
GO:0030154 cell differentiation
GO:0043403 skeletal muscle tissue regeneration
GO:0045843 negative regulation of striated muscle tissue development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048627 myoblast development
GO:0070318 positive regulation of G0 to G1 transition
GO:2000288 positive regulation of myoblast proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0044798 nuclear transcription factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt O60248
TrEMBL B4DWU7
UniProt Splice Variant
Entrez Gene 6665
UniGene Hs.731504 Hs.95582
RefSeq NM_006942
HUGO HGNC:11196
OMIM 601297
CCDS CCDS32549
HPRD 03191
IMGT
EMBL AB006867 AB025355 AC016876 AJ006222 AK301687 BC000985 BC072003 CH471108 X73039
GenPept AAH00985 AAH72003 BAA25663 BAA78784 BAG63159 CAA06920 CAA51520 EAW90156 EAW90157
RNA Seq Atlas 6665