Version 5.4
Homo sapiens Gene: HIGD1A
Summary
InnateDB Gene IDBG-28084.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIGD1A
Gene Name HIG1 hypoxia inducible domain family, member 1A
Synonyms HIG1; RCF1a;
Species Homo sapiens
Ensembl Gene ENSG00000181061
Encoded Proteins
IDBP-28086
HIG1 hypoxia inducible domain family, member 1A
IDBP-373654
HIG1 hypoxia inducible domain family, member 1A
IDBP-373657
HIG1 hypoxia inducible domain family, member 1A
IDBP-373658
HIG1 hypoxia inducible domain family, member 1A
IDBP-373661
HIG1 hypoxia inducible domain family, member 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:42757177-42804531
Strand Reverse strand
Band p22.1
Transcripts
ENST00000321331 ENSP00000319393
ENST00000431549 ENSP00000406044
ENST00000418900 ENSP00000402160
ENST00000452906 ENSP00000398064
ENST00000430190 ENSP00000408289
ENST00000470543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006950 response to stress
GO:0042149 cellular response to glucose starvation
GO:0043066 negative regulation of apoptotic process
GO:0055114 oxidation-reduction process
GO:0071456 cellular response to hypoxia
GO:0090201 negative regulation of release of cytochrome c from mitochondria
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043234 protein complex
GO:0070469 respiratory chain
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000038412
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000031731
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9Y241
TrEMBL A0A024R2M9
UniProt Splice Variant
Entrez Gene 25994
UniGene
RefSeq NM_001099669 NM_014056 NM_001099668
HUGO HGNC:29527
OMIM
CCDS CCDS43073 CCDS46806
HPRD 13651
IMGT
EMBL AF077034 AF145385 AL110233 BC000601 BC009583 BC009594 BC070277 BG400624 CH471055 CR457385
GenPept AAD27767 AAD33954 AAH00601 AAH09583 AAH09594 AAH70277 CAB53686 CAG33666 EAW64673 EAW64677
RNA Seq Atlas 25994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca