Homo sapiens Gene: SLC14A1
Summary
InnateDB Gene IDBG-2812.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC14A1
Gene Name solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Synonyms HsT1341; HUT11; JK; RACH1; RACH2; UT-B1; UT1; UTE;
Species Homo sapiens
Ensembl Gene ENSG00000141469
Encoded Proteins
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:45724127-45752520
Strand Forward strand
Band q12.3
Transcripts
ENST00000321925 ENSP00000318546
ENST00000402943 ENSP00000385320
ENST00000415427 ENSP00000412309
ENST00000436407 ENSP00000390637
ENST00000502059 ENSP00000442180
ENST00000535474 ENSP00000441998
ENST00000591541
ENST00000587601 ENSP00000465029
ENST00000589322 ENSP00000466273
ENST00000586056 ENSP00000470055
ENST00000586854
ENST00000586142 ENSP00000470476
ENST00000591642
ENST00000590246 ENSP00000468763
ENST00000586951 ENSP00000465702
ENST00000590377 ENSP00000465150
ENST00000588179 ENSP00000467898
ENST00000589891 ENSP00000466093
ENST00000589700 ENSP00000465044
ENST00000591943
ENST00000619403 ENSP00000479595
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005372 water transmembrane transporter activity
GO:0015204 urea transmembrane transporter activity
GO:0015265 urea channel activity
Biological Process
GO:0006833 water transport
GO:0015840 urea transport
GO:0055085 transmembrane transport
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL B3KXJ3 F5GWS2 G3K397 J7FHA1 K7EL30 M0QX00 Q71UV7 Q8WXW8
UniProt Splice Variant
Entrez Gene 6563
UniGene Hs.101307 Hs.600667
RefSeq NM_001128588 NM_001146036 NM_001146037 NM_015865 XM_005258332 XM_005258333 XM_006722526
HUGO HGNC:10918
OMIM 613868
CCDS CCDS11925 CCDS45860
HPRD 00195
IMGT
EMBL AC023421 AF046026 AF328890 AK127452 JN104323 JN571298
GenPept AAC69610 AAL37474 AEN14346 AFN89222 BAG54505
RNA Seq Atlas 6563