Homo sapiens Gene: SLC38A4
Summary
InnateDB Gene IDBG-28651.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC38A4
Gene Name solute carrier family 38, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139209
Encoded Proteins
solute carrier family 38, member 4
solute carrier family 38, member 4
solute carrier family 38, member 4
solute carrier family 38, member 4
solute carrier family 38, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001 [PubMed 11342143]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:46764761-46832408
Strand Reverse strand
Band q13.11
Transcripts
ENST00000266579 ENSP00000266579
ENST00000447411 ENSP00000389843
ENST00000550670 ENSP00000448186
ENST00000547477 ENSP00000450071
ENST00000546940 ENSP00000448543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015171 amino acid transmembrane transporter activity
GO:0015293 symporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Amino acid transport across the plasma membrane pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL F8VRD9
UniProt Splice Variant
Entrez Gene 55089
UniGene Hs.446077 Hs.694012
RefSeq NM_018018 NM_001143824 XM_005268997
HUGO HGNC:14679
OMIM 608065
CCDS CCDS8750
HPRD 12159
IMGT
EMBL AC008014 AC080136
GenPept
RNA Seq Atlas 55089