Version 5.4
Homo sapiens Gene: HSD17B11
Summary
InnateDB Gene IDBG-28970.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B11
Gene Name hydroxysteroid (17-beta) dehydrogenase 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198189
Encoded Proteins
IDBP-28972
hydroxysteroid (17-beta) dehydrogenase 11
IDBP-478119
hydroxysteroid (17-beta) dehydrogenase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:87336610-87391386
Strand Reverse strand
Band q22.1
Transcripts
ENST00000358290 ENSP00000351035
ENST00000507518
ENST00000512344
ENST00000502576
ENST00000507286 ENSP00000423775
ENST00000513854
ENST00000508413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0016229 steroid dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006694 steroid biosynthetic process
GO:0006710 androgen catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005811 lipid particle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029311
View Gene Order
ENSBTAG00000006307
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 51170
UniGene Hs.594923
RefSeq NM_016245
HUGO HGNC:22960
OMIM 612831
CCDS CCDS3619
HPRD 10881
IMGT
EMBL
GenPept
RNA Seq Atlas 51170

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca