Version 5.4
Homo sapiens Gene: GAS7
Summary
InnateDB Gene IDBG-29999.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAS7
Gene Name growth arrest-specific 7
Synonyms MLL/GAS7
Species Homo sapiens
Ensembl Gene ENSG00000007237
Encoded Proteins
IDBP-30001
growth arrest-specific 7
IDBP-238003
growth arrest-specific 7
IDBP-368357
growth arrest-specific 7
IDBP-368360
growth arrest-specific 7
IDBP-588351
growth arrest-specific 7
IDBP-764424
IDBP-764870
IDBP-762649
IDBP-764136
IDBP-764911
IDBP-758927
IDBP-758450
IDBP-762721
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:9910609-10198551
Strand Reverse strand
Band p13.1
Transcripts
ENST00000323816 ENSP00000322608
ENST00000396115 ENSP00000379421
ENST00000437099 ENSP00000410108
ENST00000432992 ENSP00000407552
ENST00000542249 ENSP00000443265
ENST00000585266 ENSP00000464240
ENST00000581871
ENST00000583882 ENSP00000464088
ENST00000580043 ENSP00000463551
ENST00000578655
ENST00000580865 ENSP00000463873
ENST00000579140
ENST00000581112
ENST00000579158 ENSP00000463527
ENST00000578456
ENST00000584146 ENSP00000462304
ENST00000578599 ENSP00000464494
ENST00000584389 ENSP00000462897
ENST00000580811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007050 cell cycle arrest
GO:0008360 regulation of cell shape
GO:0030041 actin filament polymerization
GO:0030182 neuron differentiation
GO:0048812 neuron projection morphogenesis
GO:0051017 actin filament bundle assembly
Cellular Component
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005884 actin filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033066
View Gene Order
ENSBTAG00000019107
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.462214 Hs.618996
RefSeq NM_001130831 NM_003644 NM_201432 NM_201433 XM_005256831 XM_005256832 XM_005256833 XM_005256834 XM_005256835
HUGO
OMIM
CCDS CCDS11152 CCDS42263 CCDS45611 CCDS58518
HPRD 16011
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca