Version 5.4
Homo sapiens Gene: USP47
Summary
InnateDB Gene IDBG-32135.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP47
Gene Name ubiquitin specific peptidase 47
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170242
Encoded Proteins
IDBP-32137
ubiquitin specific peptidase 47
IDBP-230578
ubiquitin specific peptidase 47
IDBP-604300
ubiquitin specific peptidase 47
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:11841423-11959323
Strand Forward strand
Band p15.3
Transcripts
ENST00000339865 ENSP00000339957
ENST00000305481
ENST00000399455 ENSP00000382382
ENST00000525257
ENST00000527733 ENSP00000433146
ENST00000525367
ENST00000525078
ENST00000531513
ENST00000530041
ENST00000530369
ENST00000529813
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
GO:0071987 WD40-repeat domain binding
Biological Process
GO:0006284 base-excision repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0030307 positive regulation of cell growth
GO:0034644 cellular response to UV
GO:0035520 monoubiquitinated protein deubiquitination
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
GO:0005737 cytoplasm
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059263
View Gene Order
ENSBTAG00000010919
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.577256 Hs.619539
RefSeq NM_001282659 NM_017944 XM_005252997
HUGO
OMIM
CCDS CCDS41619 CCDS60725
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca