Version 5.4
Homo sapiens Gene: GRASP
Summary
InnateDB Gene IDBG-33946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRASP
Gene Name GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000161835
Encoded Proteins
IDBP-33948
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
IDBP-583413
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
IDBP-604003
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:52006940-52015889
Strand Forward strand
Band q13.13
Transcripts
ENST00000293662 ENSP00000293662
ENST00000552963
ENST00000552049 ENSP00000449492
ENST00000546756 ENSP00000448476
ENST00000550809
ENST00000547749
ENST00000552508
ENST00000548505
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030165 PDZ domain binding
GO:0030306 ADP-ribosylation factor binding
GO:0042802 identical protein binding
Biological Process
GO:0007165 signal transduction
GO:0008104 protein localization
Cellular Component
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000531
View Gene Order
ENSBTAG00000021658
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.407202
RefSeq NM_001271856 NM_181711 XM_006719261
HUGO
OMIM
CCDS CCDS61124 CCDS8817
HPRD 17077
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca