Homo sapiens Gene: TIFA
Summary
InnateDB Gene IDBG-34438.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TIFA
Gene Name TRAF-interacting protein with forkhead-associated domain
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145365
Encoded Proteins
TRAF-interacting protein with forkhead-associated domain
TRAF-interacting protein with forkhead-associated domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
Bacterial-derived monosaccharide heptose-1,7-bisphosphate (HBP) is a pathogen-associated molecular pattern (PAMP) that activates TIFA-dependent immunity to Gram-negative bacteria
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:112274542-112285903
Strand Reverse strand
Band q25
Transcripts
ENST00000361717 ENSP00000354911
ENST00000500655 ENSP00000424231
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response (InnateDB)
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
TNFalpha pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96CG3
TrEMBL
UniProt Splice Variant
Entrez Gene 92610
UniGene Hs.310640 Hs.626166
RefSeq NM_052864
HUGO HGNC:19075
OMIM 609028
CCDS CCDS34051
HPRD 09835
IMGT
EMBL AB062110 AB097011 AB097038 AC109347 AK292900 BC014259 CH471057
GenPept AAH14259 AAY40963 BAB86902 BAC77364 BAC77391 BAF85589 EAX06273
RNA Seq Atlas 92610