Version 5.4
Mus musculus Gene: Tifa
Summary
InnateDB Gene IDBG-193164.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tifa
Gene Name TRAF-interacting protein with forkhead-associated domain
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000046688
Encoded Proteins
IDBP-193166
TRAF-interacting protein with forkhead-associated domain
IDBP-620675
TRAF-interacting protein with forkhead-associated domain
IDBP-620677
TRAF-interacting protein with forkhead-associated domain
IDBP-620678
TRAF-interacting protein with forkhead-associated domain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 26068852
[Homo sapiens] Bacterial-derived monosaccharide heptose-1,7-bisphosphate (HBP) is a pathogen-associated molecular pattern (PAMP) that activates TIFA-dependent immunity to Gram-negative bacteria
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145365:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:127789872-127832135
Strand Forward strand
Band G2
Transcripts
ENSMUST00000054483 ENSMUSP00000054036
ENSMUST00000163775 ENSMUSP00000132309
ENSMUST00000166778
ENSMUST00000164447 ENSMUSP00000126692
ENSMUST00000171621 ENSMUSP00000127700
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007249 I-kappaB kinase/NF-kappaB signaling
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145365
View Gene Order
ENSBTAG00000027655
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.31852 Mm.404642
RefSeq NM_145133 XM_006501236
OMIM
CCDS CCDS38628
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca