|Homo sapiens Gene: KRT4|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||keratin 4|
|Synonyms||CK-4; CK4; CYK4; K4; WSN1;|
|Useful resources||Stemformatics EHFPI ImmGen|
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 12:52806549-52814551|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas||3851|