Version 5.4
Homo sapiens Gene: MAPRE3
Summary
InnateDB Gene IDBG-36353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAPRE3
Gene Name microtubule-associated protein, RP/EB family, member 3
Synonyms EB3; EBF3; EBF3-S; RP3
Species Homo sapiens
Ensembl Gene ENSG00000084764
Encoded Proteins
IDBP-36357
microtubule-associated protein, RP/EB family, member 3
IDBP-294648
microtubule-associated protein, RP/EB family, member 3
IDBP-294643
microtubule-associated protein, RP/EB family, member 3
IDBP-368378
microtubule-associated protein, RP/EB family, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:26970612-27027196
Strand Forward strand
Band p23.3
Transcripts
ENST00000233121 ENSP00000233121
ENST00000405074 ENSP00000383915
ENST00000402218 ENSP00000385715
ENST00000458529 ENSP00000391705
ENST00000494788
ENST00000475633
ENST00000481222
ENST00000491354
ENST00000474367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:1903033 positive regulation of microtubule plus-end binding
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0015630 microtubule cytoskeleton
GO:0030496 midbody
GO:0035371 microtubule plus-end
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029166
View Gene Order
ENSBTAG00000008884
Not yet available
Cross-References
SwissProt Q9UPY8
TrEMBL C9JB30
UniProt Splice Variant
Entrez Gene 22924
UniGene Hs.515860
RefSeq NM_012326 XM_006711967
HUGO HGNC:6892
OMIM 605788
CCDS CCDS1731
HPRD
IMGT
EMBL AB025186 AC013472 AF288787 BC011557 CH471053 CR536523 CR541845 Y11174
GenPept AAH11557 AAK07556 AAK07557 AAY14653 BAA82958 CAA72060 CAG38760 CAG46643 EAX00660 EAX00662 EAX00663 EAX00666
RNA Seq Atlas 22924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca