Homo sapiens Gene: WDR36
Summary
InnateDB Gene IDBG-36607.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR36
Gene Name WD repeat domain 36
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134987
Encoded Proteins
WD repeat domain 36
WD repeat domain 36
WD repeat domain 36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:111091716-111130502
Strand Forward strand
Band q22.1
Transcripts
ENST00000506538 ENSP00000423067
ENST00000513710 ENSP00000424628
ENST00000505303
ENST00000515784
ENST00000504122
ENST00000612402 ENSP00000479950
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001895 retina homeostasis
GO:0006364 rRNA processing
GO:0007601 visual perception
GO:0008150 biological_process
GO:0030516 regulation of axon extension
GO:0050896 response to stimulus
Cellular Component
GO:0005575 cellular_component
GO:0005730 nucleolus
GO:0032040 small-subunit processome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
TSLP pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8NI36
TrEMBL D6RFM8
UniProt Splice Variant
Entrez Gene 134430
UniGene Hs.533237 Hs.706546
RefSeq NM_139281
HUGO HGNC:30696
OMIM 609669
CCDS CCDS4102
HPRD
IMGT
EMBL AC008572 AF385437 AK095312 BC133025 BC136517 CR749211
GenPept AAI33026 AAI36518 AAM43838 BAC04527 CAH18068
RNA Seq Atlas 134430