Version 5.4
Homo sapiens Gene: TNFAIP8
Summary
InnateDB Gene IDBG-38402.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNFAIP8
Gene Name tumor necrosis factor, alpha-induced protein 8
Synonyms GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Species Homo sapiens
Ensembl Gene ENSG00000145779
Encoded Proteins
IDBP-38404
tumor necrosis factor, alpha-induced protein 8
IDBP-479256
tumor necrosis factor, alpha-induced protein 8
IDBP-375079
tumor necrosis factor, alpha-induced protein 8
IDBP-478542
tumor necrosis factor, alpha-induced protein 8
IDBP-473767
tumor necrosis factor, alpha-induced protein 8
IDBP-484847
tumor necrosis factor, alpha-induced protein 8
IDBP-485233
tumor necrosis factor, alpha-induced protein 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:119268692-119399688
Strand Forward strand
Band q23.1
Transcripts
ENST00000274456 ENSP00000274456
ENST00000388882 ENSP00000429432
ENST00000415806 ENSP00000408534
ENST00000513374 ENSP00000427424
ENST00000504771 ENSP00000422245
ENST00000503646 ENSP00000421848
ENST00000504642 ENSP00000427160
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Biological Process
GO:0032611 interleukin-1 beta production
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000062210
View Gene Order
ENSBTAG00000014551
Not yet available
Cross-References
SwissProt O95379
TrEMBL E5RIJ3
UniProt Splice Variant
Entrez Gene 25816
UniGene Hs.656274
RefSeq XM_006714584 NM_001077654 NM_001286813 NM_001286814 NM_014350
HUGO HGNC:17260
OMIM 612111
CCDS CCDS47258 CCDS47257 CCDS68933
HPRD 18204
IMGT
EMBL AC008475 AC027320 AC035144 AF070671 AF098933 AF099935 AF099936 AK001850 AK001931 AK301281 BC005352 BC007014 CH471086 CR457137
GenPept AAC72975 AAC72976 AAC83229 AAF29435 AAH05352 AAH07014 BAG50983 BAG50994 BAH13449 CAG33418 EAW48914
RNA Seq Atlas 25816

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca